The film stars Bryan Cranston as Federal Agent Bob Mazur, who goes deep undercover as "slick, money-laundering businessman" Bob Musella to get inside Pablo Escobar's 1986 drug trafficking scene.

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The Infiltrator is based on the true story of federal agent Robert "Bob" Mazur (played by Cranston) who goes deep undercover to infiltrate Pablo Escobar’s drug trafficking world in 1986.