Manning vs. Manning will take place on WTHR, Channel 13 September 19.

The NFL released its schedule for the 2010 season Tuesday, sending Eli Manning to Indianapolis to take on big brother Peyton on Sunday night during Week Two of the season. The matchup is one of three the Colts will play on NBC’s Football Night in America. They will face the Redskins on October 17 and host San Diego at Lucas Oil Stadium on Sunday, November 28.

Indianapolis will host the Texans on Monday Night Football on November 1 and travel to Tennessee to face the Titans on Thursday, December 9 on the NFL Network.

The Colts will travel to Foxborough, Massachusetts to take on the rival Patriots on Sunday, November 21. They will open the season September 12 in Houston, facing the Texans.

9/12 at Houston 1 pm

9/19 vs. NY Giants 8:20 pm (NBC)

9/26 at Denver 4:15 pm

10/3 at Jacksonville 4:05 pm

10/10 vs. Kansas City 1 pm

10/17 at Washington 8:20 pm (NBC)

10/24 BYE

11/1 vs. Houston 8:30 pm (ESPN)

11/7 at Philadelphia 4:15 pm

11/14 vs. Cincinnati 1 pm

11/21 at New England 4:15 pm

11/28 vs. San Diego 8:20 pm

12/5 vs. Dallas 4:15 pm

12/9 at Tennessee 8:20 pm (NFL Network)

12/19 vs. Jacksonville 1 pm

12/26 at Oakland 4:05 pm

1/2 vs. Tennessee 1 pm

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